Peritoneal Mesothelioma

Peritoneal Mesothelioma rare type of neoplasm

Abdominal and retroperitoneal mesothelioma is a rare type of neoplasm that is malignant and benign. The peritoneum is a thin membrane formed by the cells around the abdominal cavity. The retroperitoneal space is an area outside this membrane.

Peritoneal mesothelioma

Peritoneal mesothelioma, or peritoneal mesothelioma, is a rare disease that is mostly malignant, but benign tumours in this area have also been found.

Symptoms of peritoneal mesothelioma: heaviness in the abdomen, pain, digestive disorders, impaired acidity, abdominal discomfort, bloating, poor digestion.

Treatment of peritoneal mesothelioma: radical removal of the tumour. It is indicated because of the high risk of malignant tumour transformation.

Peritoneal Mesothelioma

The prognosis in patients with benign peritoneal mesothelioma is good. With timely removal and follow-up after surgery, survival is high and long-term, as well as after other surgeries in a given area of ​​the body. The sooner mesothelioma is detected, the more favourable the prognosis and the lower the risk of benign neoplasm transforming into cancer. Mouthwash can cause cancer.


Benign fibrous mesothelioma is limited to pleural tumours and has a good prognosis, unlike malignant mesothelioma. Benign fibrosis mesothelioma is a rare type of tumour, but in the last 25 years, 52 cases of such tumours have been reported at the Mayo Clinic. Most patients with benign mesothelioma have had no contact with asbestos in the past.

Pathological characteristics

Macroscopically, benign mesothelioma is a thick, closed, yellow tumour whose outer surface can be vascularised by convex veins. About 70% are benign. Fibrous mesothelioma is formed on the visceral pleura and the remaining 30% on the parietal pleura. Occasionally, there is local germination of the tumour in the chest wall and lung. Histological benign mesothelioma is characterized by the presence of identical elongated spindle cells and various accumulations of collagen, as well as reticular fibres in a bunch of different sizes. It is not yet known which cells develop this tumour. Some believe that it is formed by subpleural fibroblasts; others consider it to be from mesothelial cells.

Clinical picture

Approximately 50% of patients with benign mesothelioma have no symptoms of tumour development and are detected by chest X-ray. In the other half of the patients, the most common symptoms are cough, chest pain and shortness of breath. In patients with clinical symptoms, each of these symptoms occurs in approximately 40% of cases. In 25% of patients, the temperature was observed without any sign of infection. In patients with this type of tumour, hypertrophic osteoarthritis occurs in about 20% of cases, more often with large tumours. Thus, it was present in 10 of 11 (91%) patients with a tumour greater than 7 cm in diameter and was not observed in any of the 41 patients with a smaller tumour. After surgical removal of the tumour,

Another symptom that sometimes manifests with benign fibrous mesothelioma is hypoglycaemia. Of the approximately 150 extrapancreatic tumours reported in 1975, accompanied by hypoglycaemia, 10 were benign fibrous mesothelioma. In a review of 360 cases of benign fibrous mesothelioma, hypoglycaemia was considered in 4% of cases. The mechanism of hypoglycaemia in these patients is unclear; it may be related to the uptake of glucose from the tumour and the suppression of lipolysis and liver glycogenesis by the products secreted by the tumour. Hypoglycaemia disappears after surgical removal of the tumour.

Radio logically; the tumour is a solitary, well-defined mass of undetermined shape, located in the peripheral part of the lung or near the intermediate cleft. The tumour has a lobular appearance. In 10% of cases, the tumour is accompanied by pleural effusion, but the presence or absence of effusion does not affect prognosis. The tumour can completely absorb hemithorax and move the heart and mediastinum in the opposite direction. Calcified sites in the tumour are sometimes seen.


A thoracotomy is needed to establish the diagnosis. Because there is benign fibrous mesothelioma that may be accompanied by common symptoms, radiation or chemotherapy in patients suspected of having a malignant tumour, they must be confirmed before the onset of malignancy. There is no doubt that with benign fibrous mesothelioma, the results of bronchoscopy and phlegm cytology should be negative.

Treatment and prognosis

Surgical removal of the tumour is recommended for patients with benign mesothelioma. If the tumour is in the visceral pleura, it may be necessary to remove a significant portion of the lung parenchyma. After surgical removal of the tumour, recovery is observed in about 90% of patients, in 10% of cases relapse occurs. Relapse may occur more than 10 years after the removal of the primary tumour. In this regard, patients with benign fibrous mesothelioma after surgical removal of the tumour are advised to take chest x-rays annually for early detection of tumour recurrence with a view to subsequent removal.

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