20 September 2016

The Cause Of Mesothelioma Cancer You Need To Know

The Cause Of Mesothelioma Cancer You Need To Know

The Cause Of Mesothelioma Cancer You Need To Know - Mesothelioma is a rare and deadly cancer caused by asbestos. While other risk factors can increase the chances of  developing cancer mesothelioma, asbestos is the only scientifically proven cause of disease.

How Asbestos Causes  Cancer Mesothelioma

Mesothelioma develops in the mesothelium, a thin membrane that covers the body's internal cavities and organs. It is caused by exposure to asbestos, often in the workplace environment, although exposure can also occur in the home, school, or other locations.

In the most common scenario, the asbestos fibers are inhaled, and eventually become lodged in the lining of the lungs, heart, or, abdomen causing harmful inflammation that eventually leads to the formation of tumors.  And in some cases, swallowing asbestos fibers can contribute to the type of mesothelioma that is formed in the stomach, known as peritoneal mesothelioma. Asbestos can also travel through the lymph nodes to other parts of the body, that surrounds the heart such as the pericardium,  and the mesothelial lining.

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As generally understood by researchers, asbestos can cause DNA damage, either directly or indirectly. Direct, asbestos disrupt the process of mitotic cell division, which can cause cell damage and mutations. Indirectly, asbestos can cause mesothelial cells to release reactive oxygen and nitrogen mutagenic, which also cause mutations.

The process by which asbestos causes mesothelioma can take a very long time. Generally, it takes anywhere from 10 to 50 years for mesothelioma to develop after exposure to asbestos occurred. However, in a small number of cases, the latency period is much shorter, and there have even been cases of mesothelioma are known in children and adolescents.

Some type Asbestos Mesothelioma May Cause More Frequently

Asbestos is included in the generic name for six types of silicate minerals that share common properties. Several studies have shown that certain forms of asbestos can cause mesothelioma at a greater rate than others.

One preliminary study published in 1986, showed that crocidolite asbestos is approximately 14 times more potent than other forms of asbestos when it comes to causes both pleural mesothelioma and peritoneal mesothelioma. However, the later reviews of the same data shows that the incidence of mesothelioma is based on the type of asbestos is actually closer.

The latest consensus among medical professionals is that the forms of amphibole asbestos - in particular, crocidolite - is stronger than other forms of asbestos snakes, such as chrysotile. However, both forms of asbestos are highly carcinogenic. As the EPA (Environmental Protection Agency) has been reported, there is no safe level of asbestos exposure, regardless of the type.

Other Contributing Factors and Causes 

Asbestos is the main cause of most of the cancer mesothelioma, with at least 80% of mesothelioma patients had a known history of asbestos exposure (and the rest may be exposed without their knowledge). However, from some research has shown that there are several other environmental risk factors that can contribute to the diagnosis of mesothelioma.

Asbestos As Mineral

Asbestos is a silicate mineral classes, and other silicate minerals has been associated with mesothelioma. Erionite, zeolite form, in particular has been associated with the disease, mainly based on a study of the mineral which occurs naturally in Cappadocia, Turkey.

Simian Virus 40 (SV40)

One study showed that more than half of cases of mesothelioma, patients also infected with SV40. Further studies have shown that SV40 may contribute to the development of mesothelioma, although it did not appear to cause mesothelioma alone.


Smoking itself is not the cause of mesothelioma. However, people who smoke and who are exposed to asbestos have a higher risk of lung cancer due to asbestos (different from mesothelioma malignancy).

Exposure to radiation

In some cases, patients have claimed their cancer mesothelioma caused by exposure to radiation, rather than exposure to asbestos. While the amount of radiation has been associated with the development of several types of cancer, the relationship between radiation and mesothelioma can not be confirmed.
Carbon Nanotubes

Several studies have looked at the carbon nanotube, and other high aspect ratio nanoparticles (harns), as a potential cause of mesothelioma. However, additional studies need to be completed to see different lengths, shapes, and other factors before connecting this to be the cause of mesothelioma.

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